Genetics

Genetics is about the body's genes and DNA that control our biological functions and affect the risk of various diseases. Genetic analyses are used to identify mutations, genetic variations and hereditary conditions linked to, among other things, metabolism, iron metabolism and cardiovascular health.
c187

HFE c.187 C-G

HFE c.187 C>G (H63D) is a genetic variant in the HFE gene that can affect the body's regulation of iron metabolism. The mutation is associated with milder forms of iron overload and is often analyzed together with HFE c.845 G>A (H282Y) in the investigation of hereditary hemochromatosis and elevated iron parameters.
c⁸⁴⁵

HFE c.845 G-A

HFE c.845 G>A is a genetic variant in the HFE gene that is strongly associated with hereditary hemochromatosis, an inherited disease that leads to increased absorption and storage of iron in the body. The mutation causes a change in the HFE protein (C282Y/H282Y) which can affect the body's regulation of iron metabolism and lead to elevated iron levels over time.