Parathyroid Hormone, PTH?
Parathyroid hormone, or parathyroid hormone (PTH), is a hormone produced by the parathyroid glands. The parathyroid glands are small glands located in the front of the neck, behind the thyroid gland. PTH plays a crucial role in regulating the body's calcium balance. The primary function of parathyroid hormone is to ensure that the calcium level in the blood remains within an optimal and stable range, which is essential to support various physiological processes in the body.
What is the function of parathyroid hormone?
PTH acts by releasing calcium from the bones and reducing the excretion of calcium in the urine by the kidneys. Additionally, PTH helps D-vitamin to enhance calcium absorption from the intestines, thereby increasing the calcium level in the blood.
Why is parathyroid hormone analyzed?
Parathyroid hormone analysis is conducted to assess and monitor calcium regulation in the body and to diagnose and monitor diseases and conditions that affect the parathyroid glands and calcium metabolism. Here are some of the main reasons why PTH is analyzed:
- Diagnosis of parathyroid diseases: PTH analysis is performed to diagnose diseases affecting the parathyroid glands, such as primary hyperparathyroidism (a condition in which the parathyroid glands overproduce PTH), secondary hyperparathyroidism (a complication of certain other diseases leading to elevated PTH levels), and parathyroid adenoma (a benign tumor in the parathyroid glands).
- Evaluation of calcium regulation: PTH levels help identify how well the body regulates blood calcium levels. High PTH levels may indicate an attempt to increase blood calcium levels, while low levels may indicate overproduction of calcium or problems with calcium absorption.
- Treatment monitoring: Individuals diagnosed with a parathyroid disease or other calcium-related conditions may require treatment to normalize PTH levels. PTH analysis is used to monitor treatment and adjust medication over time.
- Evaluation of kidney function: PTH analysis can also be useful in assessing kidney function since the kidneys are involved in calcium metabolism. Elevated PTH levels may indicate kidney issues.
What does an elevated parathyroid hormone level mean?
An elevated parathyroid hormone (PTH) level, also known as hyperparathyroidism, indicates that the parathyroid glands are producing too much PTH. This can be due to various causes and may have different clinical consequences depending on the circumstances.
What does a low parathyroid hormone level mean?
A low parathyroid hormone (PTH) level can indicate hypoparathyroidism, a condition in which the parathyroid glands do not produce enough PTH. This can have various causes and affects calcium regulation in a way that can be harmful.
What is the reference range for parathyroid hormone (P-PTH)?
The reference range for parathyroid hormone (PTH) in the blood may vary slightly between different laboratories and methods used for analysis. Additionally, it may vary depending on the individual's age and gender. Generally, the reference range for PTH is approximately: 2.0 - 9.3 pmol/L (Reference range is based on a fasting morning sample).