What are Hepatitis B core antibodies?Hepatitis B core antibodies are specific antibodies formed as part of the body's immune response to prior exposure to the Hepatitis B virus (HBV). These antibodies target a component of the virus known as "hepatitis B core antigen" (HBcAg).
Why are Hepatitis B core antibodies analyzed?
The analysis of Hepatitis B core antibodies is used to determine prior exposure to the Hepatitis B virus. It is a crucial part of diagnostic tests to understand infection status and assess an individual's immunity to HBV. It can also be used to differentiate between acute and chronic Hepatitis B infection.
What can high levels of Hepatitis B core antibodies indicate?
High levels of Hepatitis B core antibodies can indicate prior exposure to HBV and developed immunity to the virus. It can also occur in individuals with chronic Hepatitis B, especially if they have a concurrent positive marker for ongoing infection, such as HBV DNA (quantitative analysis of HBV DNA).
What can low levels of Hepatitis B core antibodies indicate?
Low levels of Hepatitis B core antibodies can indicate the absence of prior exposure to HBV. It can also occur in individuals who have recently been infected with Hepatitis B because antibody levels may take time to develop to measurable levels.
What is the relevance of Hepatitis B core Antibodies to IVF treatment?
Prior to in vitro fertilization (IVF) treatment or other forms of assisted reproduction, it is common to test for Hepatitis B and other infections as part of the medical evaluation. This is done to ensure a safe pregnancy and minimize the risk of transmitting infections to the unborn child. Determining an individual's Hepatitis B infection status is crucial for taking appropriate precautions during IVF treatment to protect both the prospective mother and the unborn child.