IgG Subclasses - Gain Deeper Insight into Your Immune System
Do you experience recurring infections or suspect that your immune system isn’t functioning optimally? A blood test measuring IgG subclasses can provide a more detailed picture of your immune system's capacity. By analyzing the levels of the four subclasses—IgG1, IgG2, IgG3, and IgG4—you can potentially detect deficiencies that may be affecting your health. The blood test helps identify immune dysfunctions and provides a basis for the right treatment, such as targeted vaccinations or other interventions.
When Is an IgG Subclass Analysis Recommended?
An IgG subclass analysis is particularly useful for those looking for a deeper investigation of their immune system. The analysis includes the following markers: IgG1, IgG2, IgG3, and IgG4. By examining these subclasses, you can identify specific immune deficiencies that may increase the risk of infections, allergies, or autoimmune diseases. The analysis can also be a valuable tool in investigating chronic inflammatory conditions, with results leading to more tailored treatment strategies.
IgG-1
The most common subclass, which fights protein antigens from viruses and bacteria.
Importance: Protects against infections such as the flu and pneumonia.
Practical Advice: Low levels may indicate an immune deficiency, making testing important for recurring infections.
IgG-2
Specializes in fighting bacteria with polysaccharides on their surface, which cause respiratory infections.
Importance: Low levels increase the risk of bacterial infections, such as sinusitis and pneumonia.
Practical Advice: Vaccinations can boost IgG2 and strengthen the immune response.
IgG-3
Effective in activating the complement system to eliminate pathogens.
Importance: Enhances the body's ability to quickly combat infections.
Practical Advice: Testing IgG3 can provide insight into the efficiency of your immune system.
IgG-4
Regulates the immune response and is associated with long-term inflammatory conditions.
Importance: Elevated levels can indicate chronic inflammation or autoimmune diseases.
Practical Advice: Test IgG4 when suspecting allergies or inflammation.