Liver

The liver is one of the body’s most vital organs and plays a central role in metabolism, detoxification, and the production of important proteins. It has a unique ability to regenerate and is essential for the body’s balance and overall health.

Quick version

What is the liver?

The liver is the largest internal organ in the human body and is located on the right side of the upper abdomen, just below the diaphragm. It weighs about 1.5 kg and has over 500 known functions, including filtering blood, producing bile, and storing nutrients.

The liver and its functions

The liver converts nutrients from the food we eat into energy, produces important proteins such as blood clotting factors, and stores vitamins and minerals. It also plays a crucial role in the body’s immune defense by neutralizing bacteria, viruses, and toxins that pass from the intestine into the bloodstream. Thanks to its versatility, the liver is essential for maintaining the body’s balance and health. Without the liver’s functions, energy metabolism, blood composition, and the body’s detoxification system would not function properly.

The liver and metabolism

By breaking down carbohydrates, fats, and proteins, the liver regulates the body’s energy balance. It controls blood sugar levels by storing and releasing glucose as needed.

Detoxification function

The liver is the body’s most important detoxification organ. It breaks down medications, alcohol, and toxins, which are then excreted through bile or urine.

Common conditions and diseases

Pain in the liver is rarely felt directly, but liver diseases can cause symptoms such as fatigue, yellowing of the skin (jaundice), and discomfort in the upper abdomen. Common conditions include fatty liver, hepatitis, cirrhosis, and liver cancer.

Examination and diagnosis

Liver diseases are investigated through blood test (liver function test), ultrasound, CT scans, and sometimes liver biopsy. These methods help identify inflammation, fibrosis, and tumors.

Relevant symptoms

  • Fatigue
  • Jaundice (yellow skin and eyes)
  • Dark urine
  • Pale stools
  • Abdominal swelling (ascites)
  • Nausea

Related conditions and diagnoses

  • Hepatitis A, B, and C
  • Fatty liver (NAFLD, alcohol-related)
  • Cirrhosis of the liver
  • Liver cancer
  • Biliary diseases

Questions and answers

The liver is located on the right side of the upper abdomen, just below the diaphragm and next to the stomach. It is positioned so that it is well protected by the ribs.

The liver has many functions, including breaking down nutrients, producing proteins for blood clotting, storing vitamins, and regulating blood sugar. It also detoxifies the body from harmful substances.

The liver itself has no pain nerve endings, so pain often comes from the capsule surrounding the liver or from nearby organs. Symptoms may include pressure, discomfort, or swelling in the upper abdomen.

Fatty liver means that fat accumulates in the liver cells. It can be caused by overweight, alcohol, or metabolic diseases and may eventually lead to inflammation and cirrhosis.

Liver cirrhosis is a condition where healthy liver tissue is gradually replaced by scar tissue (fibrosis). This makes the liver stiff and reduces its function. As the scarring spreads, blood flow through the liver is impaired, and its ability to filter blood, produce proteins, and store nutrients decreases significantly. The most common causes of cirrhosis are long-term alcohol use, chronic viral hepatitis (especially hepatitis B and C), fatty liver that has developed into inflammation (NASH), and certain hereditary diseases. The condition usually develops slowly over several years and may initially be symptom-free. Common symptoms of cirrhosis include fatigue, jaundice, abdominal swelling, easy bleeding, weight loss, and in more severe cases, confusion due to the buildup of toxins in the blood (hepatic encephalopathy). Cirrhosis also increases the risk of liver cancer.

Yes, the liver has a unique ability to regenerate after injury. If the damage is not too extensive, it can heal once the harmful factor has been removed.

You should seek medical care if you experience symptoms such as prolonged fatigue, jaundice (yellow skin and eyes), dark urine, pale stools, unexplained weight loss, or abdominal swelling. Itching, a tendency to bleed, nausea, or loss of appetite can also be signs of liver disease. It is especially important to contact healthcare quickly if symptoms develop suddenly or worsen. Early investigation with blood tests and imaging can detect diseases at a treatable stage and prevent complications such as cirrhosis or liver cancer.

Tests related to Liver

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Liver Check Test
  • Health check for your liver function
  • Analysis of relevant liver markers
  • Get more insight into your liver health

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