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Sampling fee?

The sample collection fee is a fixed cost that refers to the visit to the clinic where you submit your sample. The fee is not affected by how many tests you have ordered, but varies depending on the order value:

  • For order values under SEK 350, the sampling fee is SEK 129.
  • For order values between SEK 350 and SEK 1000, the fee is SEK 59.
Free sampling fee

For purchases over 1000 SEK, the sampling fee is included.

ATF

Vitamin E

Alpha Tocopherol

S-alpha-Tocopherol is the primary form of vitamin E, a fat-soluble vitamin with antioxidant properties that protect cells from oxidative stress and support the immune system. The analysis is important in cases of suspected deficiency, toxicity, or malabsorption.

What is s-alpha-tocopherol?

S-alpha-Tocopherol is the primary form of vitamin E measured in serum. Vitamin E is a fat-soluble vitamin that acts as a powerful antioxidant, protecting cell membranes from oxidative damage caused by free radicals. It also plays a critical role in supporting the immune system, nerve function, and many other physiological processes.

Analysis of S-alpha-tocopherol

When analyzing blood samples, the levels of alpha-tocopherol, the main form of vitamin E, are measured in serum. Vitamin E is a fat-soluble vitamin with antioxidant properties that protect cell membranes from damage caused by free radicals. The test is conducted using a blood sample analyzed with chromatography (LC) and UV detection to ensure accurate and reliable results.

The s-alpha-tocopherol test is primarily used to evaluate vitamin E status, particularly in cases of suspected deficiency or toxicity. The test is also relevant in investigations of malabsorption, such as in cystic fibrosis, cholestasis, or protein-losing enteropathy. In addition to S-alpha-Tocopherol, the analysis also provides results for S-Retinol (Vitamin A), offering a broader view of fat-soluble vitamins in the body.

Abnormal test results and references

Abnormal levels of S-alpha-Tocopherol may indicate various medical conditions:

  • Low levels: May result from malabsorption, chronic conditions affecting fat uptake, or insufficient dietary intake. Symptoms can include muscle weakness, hemolytic anemia, and neurological problems.
  • High levels: May occur due to excessive intake of vitamin E supplements, potentially leading to inhibited vitamin K metabolism and increased bleeding risk.

Common causes of vitamin e deficiency

Vitamin E deficiency is rare in healthy individuals but may occur under the following conditions:

  • Chronic diseases affecting fat absorption, such as cholestasis, pancreatitis, or cystic fibrosis.
  • Loss of fat-soluble vitamins due to protein loss in the intestine.
  • Prematurity in infants, where deficiency can cause hemolysis and neurological symptoms.

Reference intervals for s-alpha-tocopherol:

  • 0–18 years: 12–30 µmol/L
  • Adults: 12–42 µmol/L

Lipemic samples may produce unreliable results; fasting is recommended to minimize interference.

What conditions or diseases are associated with abnormal levels of S-alpha-tocopherol?

S-alpha-Tocopherol is associated with several medical conditions, particularly those involving fat malabsorption and oxidative stress:

  • Cystic Fibrosis: A chronic condition affecting the lungs and digestion, leading to fat malabsorption.
  • Cholestasis: Blocked or impaired bile flow, reducing the absorption of fat-soluble vitamins like vitamin E.
  • Protein-losing Enteropathy: A condition where proteins and fat-soluble vitamins are lost through the intestines.
  • Impaired Immune Function: Low levels of vitamin E can reduce the body’s ability to fight infections.
  • Hemolytic Anemia: Can occur in severe vitamin E deficiency, especially in premature infants.

Regular monitoring of s-alpha-tocopherol is particularly important in patients at risk of malabsorption or those undergoing vitamin e therapy.

Tests containing the marker Alpha Tocopherol

Vitamin tests

Vitamin tests


ATF
  • Measures your vitamin E levels.
  • Blood test for suspected vitamin E deficiency.
  • Analysis of S-alpha-tocopherol.
  • Get insights into your vitamin E levels.

895 kr

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